Page 5 - Orsiro_Brochure_April_11

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protection
passive
Sealed with a semi conductive barrier
Once the stent is introduced into the body, water can immediately interact with the metal
surface. PROBIO
®
coating is a silicon carbide, semi conductive sealant, that greatly reduces
the interaction between tissue or blood with the metallic surface of the stent.
In vivo studies have shown up to a 96 % reduction of allergenic metal ions when the stent
surface is coated with silicon carbide.
1
Quick facts
BIOlute
®
is based on a high molecular weight Poly-L-Lactic Acid
(PLLA) – a material that degrades by hydrolysis. The degradation
process leads to reduction of polymer chain lengths and ends up
in the production of CO
2
and water following the Krebs cycle.
There is a long history of using PLLA in medical applications.
Concentration in ng/l
0
5 000
10 000
15 000
Competitor A
cobalt nickel alloy
Competitior B
cobalt chromium alloy
PRO-Kinetic Energy
with PROBIO
®
coating
20 000
25 000
Cobalt
Nickel
Tungsten
Chromium
1
Data on file at BIOTRONIK.